Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. [electronic resource]
- Diabetes Dec 2003
- 2975-83 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0012-1797
10.2337/diabetes.52.12.2975 doi
Cells, Cultured Collagen Type I--biosynthesis Collagen Type III--biosynthesis Connective Tissue Growth Factor Dose-Response Relationship, Drug Drug Synergism Fibroblasts--drug effects Glucose--administration & dosage Humans Immediate-Early Proteins--biosynthesis Insulin-Like Growth Factor I--biosynthesis Intercellular Signaling Peptides and Proteins--biosynthesis Kidney--metabolism Recombinant Proteins--pharmacology Transforming Growth Factor beta--pharmacology Transforming Growth Factor beta1