Tan, Miao <br/><br/>
Phosphoinositide 3-kinase cascade facilitates mu-opioid desensitization in sensory neurons by altering G-protein-effector interactions.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  Nov 2003 
 - 10292-301 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Calcium--metabolism<br/>Calcium Channels--drug effects<br/>Cells, Cultured<br/>Enkephalin, Ala(2)-MePhe(4)-Gly(5)---pharmacology<br/>Enzyme Inhibitors--pharmacology<br/>GTP-Binding Proteins--metabolism<br/>Ganglia, Spinal--cytology<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Mutant Strains<br/>Mitogen-Activated Protein Kinases--antagonists & inhibitors<br/>Neurons, Afferent--cytology<br/>PTEN Phosphohydrolase<br/>Patch-Clamp Techniques<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phosphoric Monoester Hydrolases--deficiency<br/>Protein Serine-Threonine Kinases<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-akt<br/>Receptors, Opioid, mu--agonists<br/>Signal Transduction--drug effects<br/>Tumor Suppressor Proteins--deficiency