B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF factors in scleroderma fibroblasts. [electronic resource]
- The Biochemical journal Mar 2004
- 609-16 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1470-8728
10.1042/BJ20031110 doi
Binding Sites CCAAT-Binding Factor--metabolism Cell Cycle Proteins Cell Line Cell Nucleus--metabolism Collagen Type I--genetics Collagen Type I, alpha 1 Chain DNA-Binding Proteins--chemistry Dermis--cytology Down-Regulation Female Fibroblasts--metabolism Gene Silencing Humans Macromolecular Substances Male Promoter Regions, Genetic Protein Structure, Tertiary Repressor Proteins--metabolism Scleroderma, Systemic--genetics Sp1 Transcription Factor--metabolism Trans-Activators--chemistry