TY  - GEN
AU  - Bolton,Ann E
AU  - Peng,Bin
AU  - Hubert,Martine
AU  - Krebs-Brown,Axel
AU  - Capdeville,Renaud
AU  - Keller,Urs
AU  - Seiberling,Michael
TI  - Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects
SN  - 0344-5704
PY  - 2004///0309
KW  - Adult
KW  - Antibiotics, Antitubercular
KW  - adverse effects
KW  - Antineoplastic Agents
KW  - Area Under Curve
KW  - Aryl Hydrocarbon Hydroxylases
KW  - biosynthesis
KW  - Benzamides
KW  - Biotransformation
KW  - Cytochrome P-450 CYP3A
KW  - Drug Interactions
KW  - Enzyme Induction
KW  - drug effects
KW  - Female
KW  - Half-Life
KW  - Humans
KW  - Hydrocortisone
KW  - blood
KW  - Imatinib Mesylate
KW  - Male
KW  - Oxidoreductases, N-Demethylating
KW  - Piperazines
KW  - Pyrimidines
KW  - Rifampin
N1  - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00280-003-0722-9
ER  -