TY  - GEN
AU  - Hook,Vivian Y H
AU  - Reisine,Terry D
TI  - Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway
SN  - 0360-4012
PY  - 2003///1219
KW  - Alzheimer Disease
KW  - genetics
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Peptides
KW  - metabolism
KW  - Animals
KW  - Aspartic Acid Endopeptidases
KW  - Cells, Cultured
KW  - Chromaffin Cells
KW  - drug effects
KW  - Cysteine Endopeptidases
KW  - Cysteine Proteinase Inhibitors
KW  - pharmacology
KW  - Dithiothreitol
KW  - Endopeptidases
KW  - Extracellular Space
KW  - Glutathione
KW  - Leucine
KW  - analogs & derivatives
KW  - Mice
KW  - Mice, Knockout
KW  - Mutation
KW  - Neurons
KW  - Nicotine
KW  - Nicotinic Agonists
KW  - Peptide Fragments
KW  - Potassium Chloride
KW  - Secretory Vesicles
KW  - Substrate Specificity
KW  - Time Factors
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1002/jnr.10784
ER  -