Impaired host defense to Klebsiella pneumoniae infection in mice treated with the PDE4 inhibitor rolipram. [electronic resource]
- British journal of pharmacology Nov 2003
- 855-62 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0007-1188
10.1038/sj.bjp.0705517 doi
3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors Animals Cyclic Nucleotide Phosphodiesterases, Type 4 Cytokines--immunology Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Female Klebsiella Infections--immunology Klebsiella pneumoniae--immunology Mice Mice, Inbred BALB C Neutrophil Infiltration--drug effects Rolipram--pharmacology