Stubdal, Hilde <br/><br/>
A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38.  [electronic resource] 

 -  Cancer research  Oct 2003 
 - 6900-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenoviridae--genetics<br/>Animals<br/>Camptothecin--analogs & derivatives<br/>Carboxylesterase--genetics<br/>Colonic Neoplasms--enzymology<br/>Female<br/>Humans<br/>Irinotecan<br/>Mice<br/>Mice, Nude<br/>Prodrugs--pharmacokinetics<br/>Rabbits<br/>Transgenes<br/>Virus Replication<br/>Xenograft Model Antitumor Assays