TY - GEN AU - Uckun,Fatih M AU - Vassilev,Alexei AU - Bartell,Steve AU - Zheng,Yaguo AU - Mahajan,Sandeep AU - Tibbles,Heather E TI - The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism SN - 1042-8194 PY - 2004///0323 KW - Adenosine Diphosphate KW - pharmacology KW - Agammaglobulinaemia Tyrosine Kinase KW - Amides KW - Animals KW - Aspirin KW - Bleeding Time KW - Catalytic Domain KW - drug effects KW - Collagen KW - antagonists & inhibitors KW - Drug Design KW - Drug Evaluation, Preclinical KW - Enzyme Inhibitors KW - Fibrinolytic Agents KW - Humans KW - Janus Kinase 3 KW - Male KW - Mice KW - Mice, Inbred ICR KW - Nitriles KW - Peptide Fragments KW - Platelet Activation KW - Platelet Aggregation KW - Platelet Aggregation Inhibitors KW - Platelet Membrane Glycoproteins KW - Protein-Tyrosine Kinases KW - Pulmonary Embolism KW - chemically induced KW - Quinazolines KW - Receptors, Collagen KW - Signal Transduction KW - Thrombin KW - Thromboembolism KW - Thromboplastin KW - toxicity N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.3109/10428190309178781 ER -