TY - GEN AU - Hacein-Bey-Abina,S AU - Von Kalle,C AU - Schmidt,M AU - McCormack,M P AU - Wulffraat,N AU - Leboulch,P AU - Lim,A AU - Osborne,C S AU - Pawliuk,R AU - Morillon,E AU - Sorensen,R AU - Forster,A AU - Fraser,P AU - Cohen,J I AU - de Saint Basile,G AU - Alexander,I AU - Wintergerst,U AU - Frebourg,T AU - Aurias,A AU - Stoppa-Lyonnet,D AU - Romana,S AU - Radford-Weiss,I AU - Gross,F AU - Valensi,F AU - Delabesse,E AU - Macintyre,E AU - Sigaux,F AU - Soulier,J AU - Leiva,L E AU - Wissler,M AU - Prinz,C AU - Rabbitts,T H AU - Le Deist,F AU - Fischer,A AU - Cavazzana-Calvo,M TI - LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 SN - 1095-9203 PY - 2003///1106 KW - Adaptor Proteins, Signal Transducing KW - Clinical Trials as Topic KW - Clone Cells KW - physiology KW - DNA-Binding Proteins KW - genetics KW - Gene Expression Regulation KW - Gene Transfer Techniques KW - Genetic Therapy KW - adverse effects KW - Genetic Vectors KW - Hematopoietic Stem Cell Transplantation KW - Hematopoietic Stem Cells KW - Humans KW - Infant KW - LIM Domain Proteins KW - Leukemia-Lymphoma, Adult T-Cell KW - etiology KW - Metalloproteins KW - Mutagenesis, Insertional KW - Promoter Regions, Genetic KW - Proto-Oncogene Mas KW - Proto-Oncogene Proteins KW - Proto-Oncogenes KW - Receptors, Interleukin-2 KW - Retroviridae KW - Severe Combined Immunodeficiency KW - therapy KW - T-Lymphocytes KW - Transcription, Genetic KW - Virus Integration KW - Virus Replication N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1088547 ER -