TY - GEN AU - Phetsuksiri,Benjawan AU - Jackson,Mary AU - Scherman,Hataichanok AU - McNeil,Michael AU - Besra,Gurdyal S AU - Baulard,Alain R AU - Slayden,Richard A AU - DeBarber,Andrea E AU - Barry,Clifton E AU - Baird,Mark S AU - Crick,Dean C AU - Brennan,Patrick J TI - Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis SN - 0021-9258 PY - 2004///0210 KW - Amino Acid Sequence KW - Antitubercular Agents KW - pharmacology KW - Blotting, Western KW - Cell Membrane KW - enzymology KW - Cell-Free System KW - Chromatography, Gas KW - Cloning, Molecular KW - Dose-Response Relationship, Drug KW - Electrophoresis, Polyacrylamide Gel KW - Fatty Acid Desaturases KW - genetics KW - Fatty Acids KW - metabolism KW - Models, Chemical KW - Molecular Sequence Data KW - Mycobacterium bovis KW - Mycobacterium tuberculosis KW - Mycolic Acids KW - Oleic Acid KW - Phenylthiourea KW - analogs & derivatives KW - Recombinant Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sequence Homology, Amino Acid KW - Stearic Acids KW - Stearoyl-CoA Desaturase KW - Time Factors N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M311209200 ER -