GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function. [electronic resource]
- Brain research. Molecular brain research Oct 2003
- 10-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0169-328X
10.1016/s0169-328x(03)00330-9 doi
Animals Astrocytes--immunology Brain--immunology Cell Line GTP-Binding Protein alpha Subunits, Gi-Go--metabolism GTP-Binding Protein alpha Subunits, Gq-G11--metabolism Gene Expression Regulation--drug effects Glucose--immunology Humans Immunohistochemistry Leukocytes--immunology Lipopolysaccharides--immunology Male Neuroimmunomodulation--immunology Protein Subunits--genetics RNA, Messenger--metabolism Rats Receptors, G-Protein-Coupled--genetics Receptors, Immunologic--genetics Receptors, Purinergic P2--genetics Receptors, Purinergic P2Y Up-Regulation--immunology Uridine Diphosphate--immunology