TY - GEN AU - Small,George W AU - Somasundaram,Sivagurunathan AU - Moore,Dominic T AU - Shi,Yue Y AU - Orlowski,Robert Z TI - Repression of mitogen-activated protein kinase (MAPK) phosphatase-1 by anthracyclines contributes to their antiapoptotic activation of p44/42-MAPK SN - 0022-3565 PY - 2004///0129 KW - Animals KW - Anthracyclines KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Breast Neoplasms KW - enzymology KW - Cell Line, Tumor KW - Clone Cells KW - Dual Specificity Phosphatase 1 KW - Enzyme Activation KW - Enzyme Inhibitors KW - Epithelial Cells KW - Female KW - Fluorescent Antibody Technique KW - Gene Silencing KW - Humans KW - Luciferases KW - biosynthesis KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinase 3 KW - Mitogen-Activated Protein Kinases KW - metabolism KW - Phosphorylation KW - Promoter Regions, Genetic KW - Protein Phosphatase 1 KW - Protein Tyrosine Phosphatases KW - antagonists & inhibitors KW - RNA, Messenger KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Transcription, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/jpet.103.055806 ER -