TY - GEN AU - Kim,In Jong AU - Ullrich,Thomas AU - Janetka,James W AU - Furness,M Scott AU - Jacobson,Arthur E AU - Rothman,Richard B AU - Dersch,Christina M AU - Flippen-Anderson,Judith L AU - George,Clifford AU - Rice,Kenner C TI - Diaryldimethylpiperazine ligands with mu- and delta-opioid receptor affinity: Synthesis of (+)-4-[(alphaR)-alpha-(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide and (-)-4-[(alphaR)-alpha-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide SN - 0968-0896 PY - 2004///0420 KW - Animals KW - Benzamides KW - chemical synthesis KW - Brain KW - metabolism KW - Cell Membrane KW - Crystallography, X-Ray KW - Guinea Pigs KW - Ligands KW - Molecular Conformation KW - Molecular Structure KW - Piperazines KW - Radioligand Assay KW - Rats KW - Receptors, Opioid, delta KW - agonists KW - Receptors, Opioid, mu KW - Stereoisomerism KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s0968-0896(03)00496-6 ER -