TY  - GEN
AU  - She,Qing-Bai
AU  - Solit,David
AU  - Basso,Andrea
AU  - Moasser,Mark M
TI  - Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling
SN  - 1078-0432
PY  - 2004///0520
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Chromones
KW  - pharmacology
KW  - Down-Regulation
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Inhibitors
KW  - Epidermal Growth Factor
KW  - antagonists & inhibitors
KW  - Female
KW  - Gefitinib
KW  - Genes, Tumor Suppressor
KW  - Humans
KW  - Morpholines
KW  - Phosphatidylinositol 3-Kinases
KW  - metabolism
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphoric Monoester Hydrolases
KW  - genetics
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Quinazolines
KW  - Receptor, ErbB-2
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Signal Transduction
KW  - Transfection
KW  - Tumor Cells, Cultured
N1  - Publication Type: Comparative Study; Journal Article
ER  -