Kawasaki, Hiroki

Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis. [electronic resource] - Oncogene Oct 2003 - 6839-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1206903 doi


Aged
Amino Acid Motifs
Arthritis, Rheumatoid--genetics
CDC2 Protein Kinase--drug effects
Cell Cycle Proteins
Cells, Cultured
Curcumin--pharmacology
Enzyme Inhibitors--pharmacology
Gene Expression Regulation, Enzymologic
HeLa Cells
Humans
Middle Aged
Mitosis--physiology
Molecular Sequence Data
Nuclear Proteins--genetics
Phosphorylation
Ploidies
Promoter Regions, Genetic
Protein-Tyrosine Kinases--drug effects
Proto-Oncogene Proteins c-fos--drug effects
Substrate Specificity
Synovial Membrane--pathology
Transcription Factor AP-1--chemistry
Transcriptional Activation