Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks. [electronic resource]
- The Journal of cell biology Sep 2003
- 1197-209 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9525
10.1083/jcb.200304016 doi
Adenosine Triphosphatases--physiology Apoptosis--physiology BRCA1 Protein--physiology Bloom Syndrome--pathology Cell Cycle Proteins--physiology Cell Division--physiology Cell Line, Transformed Cells, Cultured DNA Helicases--physiology DNA Repair--physiology DNA Replication--physiology DNA-Binding Proteins Etoposide--pharmacology Fibroblasts--cytology G1 Phase--physiology Humans Nuclear Proteins--physiology Nucleic Acid Synthesis Inhibitors--pharmacology Phenotype RecQ Helicases S Phase--physiology Telomerase--genetics Tumor Suppressor Protein p53--physiology