TY  - GEN
AU  - Huang,Hsueh-Meei
AU  - Ou,Hsiu-Chong
AU  - Xu,Hui
AU  - Chen,Huan-Lian
AU  - Fowler,Corinne
AU  - Gibson,Gary E
TI  - Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death
SN  - 0360-4012
PY  - 2003///1216
KW  - Animals
KW  - Caspase 3
KW  - Caspases
KW  - metabolism
KW  - Cell Death
KW  - drug effects
KW  - Cell Membrane Permeability
KW  - Chromatin
KW  - Cyclosporine
KW  - pharmacology
KW  - Cytochromes c
KW  - Ion Channels
KW  - antagonists & inhibitors
KW  - Keto Acids
KW  - Ketoglutarate Dehydrogenase Complex
KW  - L-Lactate Dehydrogenase
KW  - Matrix Metalloproteinases
KW  - Membrane Potentials
KW  - Mitochondria
KW  - Mitochondrial Membrane Transport Proteins
KW  - Mitochondrial Permeability Transition Pore
KW  - Necrosis
KW  - Neurodegenerative Diseases
KW  - enzymology
KW  - Neurons
KW  - PC12 Cells
KW  - Protein Transport
KW  - Rats
KW  - Reactive Oxygen Species
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1002/jnr.10756
ER  -