Huang, Hsueh-Meei <br/><br/>
Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.  [electronic resource] 

 -  Journal of neuroscience research  Oct 2003 
 - 309-17 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0360-4012 
<br/><br/><label>Standard No.: </label>10.1002/jnr.10756  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Caspase 3<br/>Caspases--metabolism<br/>Cell Death--drug effects<br/>Cell Membrane Permeability--drug effects<br/>Chromatin--drug effects<br/>Cyclosporine--pharmacology<br/>Cytochromes c--metabolism<br/>Ion Channels--antagonists & inhibitors<br/>Keto Acids--pharmacology<br/>Ketoglutarate Dehydrogenase Complex--antagonists & inhibitors<br/>L-Lactate Dehydrogenase--metabolism<br/>Matrix Metalloproteinases--drug effects<br/>Membrane Potentials--drug effects<br/>Mitochondria--drug effects<br/>Mitochondrial Membrane Transport Proteins<br/>Mitochondrial Permeability Transition Pore<br/>Necrosis<br/>Neurodegenerative Diseases--enzymology<br/>Neurons--drug effects<br/>PC12 Cells<br/>Protein Transport--drug effects<br/>Rats<br/>Reactive Oxygen Species--metabolism