Association between a specific Pneumocystis jiroveci dihydropteroate synthase mutation and failure of pyrimethamine/sulfadoxine prophylaxis in human immunodeficiency virus-positive and -negative patients. [electronic resource]
- The Journal of infectious diseases Oct 2003
- 1017-23 p. digital
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
0022-1899
10.1086/378239 doi
Adolescent Adult Aged Alleles Anti-Bacterial Agents Antibiotic Prophylaxis--methods Bronchoalveolar Lavage Fluid--microbiology Child Child, Preschool Dihydropteroate Synthase--genetics Drug Combinations Drug Therapy, Combination--pharmacology Female HIV Infections--immunology HIV-1 Humans Immunocompromised Host Male Middle Aged Pneumocystis--enzymology Pneumocystis Infections--immunology Point Mutation Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational Pyrimethamine--pharmacology Sulfadoxine--pharmacology