TY - GEN AU - Kaul,Siddharth AU - Kanthasamy,Arthi AU - Kitazawa,Masashi AU - Anantharam,Vellareddy AU - Kanthasamy,Anumantha G TI - Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration SN - 0953-816X PY - 2003///1205 KW - 1-Methyl-4-phenylpyridinium KW - toxicity KW - Animals KW - Apoptosis KW - drug effects KW - Benzimidazoles KW - metabolism KW - Caspase 3 KW - Caspase 9 KW - Caspase Inhibitors KW - Caspases KW - Cell Line KW - Coumarins KW - Cytochromes c KW - DNA Fragmentation KW - Dopamine KW - Dose-Response Relationship, Drug KW - Drug Interactions KW - Enzyme Inhibitors KW - pharmacology KW - Flow Cytometry KW - instrumentation KW - Free Radical Scavengers KW - Gene Expression KW - Herbicides KW - In Vitro Techniques KW - Manganese Compounds KW - Mesencephalon KW - cytology KW - Metalloporphyrins KW - Nerve Degeneration KW - chemically induced KW - Organometallic Compounds KW - Oxidative Stress KW - Precipitin Tests KW - Protein Kinase C KW - classification KW - Protein Kinase C-delta KW - Rats KW - Reactive Oxygen Species KW - Time Factors KW - Transfection KW - methods N1 - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1046/j.1460-9568.2003.02864.x ER -