TY - GEN AU - Abe,Yasuyuki AU - Aoyagi,Atsushi AU - Hara,Takao AU - Abe,Kazumi AU - Yamazaki,Reina AU - Kumagae,Yoshihiro AU - Naruto,Shunji AU - Koyama,Kazuo AU - Marumoto,Shinji AU - Tago,Keiko AU - Toda,Narihiro AU - Takami,Kazuko AU - Yamada,Naho AU - Ori,Mayuko AU - Kogen,Hiroshi AU - Kaneko,Tsugio TI - Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease SN - 1347-8613 PY - 2004///0709 KW - Acetylcholinesterase KW - metabolism KW - Administration, Oral KW - Aging KW - drug effects KW - Alzheimer Disease KW - drug therapy KW - Animals KW - Carbamates KW - chemistry KW - Carrier Proteins KW - antagonists & inhibitors KW - Cholinesterase Inhibitors KW - Fumarates KW - Hippocampus KW - Male KW - Maze Learning KW - Membrane Glycoproteins KW - Membrane Transport Proteins KW - Memory KW - Mice KW - Microdialysis KW - Motor Activity KW - Nerve Tissue Proteins KW - Rats KW - Rats, Inbred F344 KW - Rats, Sprague-Dawley KW - Rats, Wistar KW - Serotonin Plasma Membrane Transport Proteins N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1254/jphs.93.95 ER -