TY - GEN AU - Yakovlev,Gennady I AU - Mitkevich,Vladimir A AU - Shaw,Kevin L AU - Trevino,Saul AU - Newsom,Stephanie AU - Pace,C Nick AU - Makarov,Alexander A TI - Contribution of active site residues to the activity and thermal stability of ribonuclease Sa SN - 0961-8368 PY - 2004///0519 KW - Arginine KW - chemistry KW - Calorimetry, Differential Scanning KW - Catalysis KW - Catalytic Domain KW - genetics KW - Dinucleoside Phosphates KW - metabolism KW - Enzyme Stability KW - Glutamic Acid KW - Glutamine KW - Histidine KW - Hydrogen-Ion Concentration KW - Isoenzymes KW - Kinetics KW - Mutagenesis, Site-Directed KW - Poly I KW - Recombinant Proteins KW - Ribonucleases KW - Substrate Specificity KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1110/ps.03176803 ER -