Opposing signals from pathogen-associated molecular patterns and IL-10 are critical for optimal dendritic cell induction of in vivo humoral immunity to Streptococcus pneumoniae. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Oct 2003
- 3508-19 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.171.7.3508 doi
Adjuvants, Immunologic--physiology Adoptive Transfer Animals Antibodies, Bacterial--biosynthesis Apoptosis--immunology Autocrine Communication--immunology Bacterial Proteins--immunology Bone Marrow Cells--cytology Cell Differentiation--immunology Cytokines--antagonists & inhibitors Dendritic Cells--cytology Dose-Response Relationship, Immunologic Down-Regulation--immunology Growth Inhibitors--physiology Hot Temperature Immunoglobulin G--biosynthesis Immunoglobulin Isotypes--biosynthesis Immunophenotyping Interleukin-10--physiology Interleukin-12--antagonists & inhibitors Mice Mice, Inbred BALB C Mice, Inbred C57BL Polysaccharides, Bacterial--immunology Signal Transduction--immunology Streptococcus pneumoniae--immunology Time Factors Vaccines, Inactivated--immunology