Identification of C8-methylguanine in the hydrolysates of DNA from rats administered 1,2-dimethylhydrazine. Evidence for in vivo DNA alkylation by methyl radicals. [electronic resource]
- The Journal of biological chemistry Oct 1992
- 21524-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
1,2-Dimethylhydrazine Alkylation Animals Carcinogens--toxicity Chromatography, High Pressure Liquid Chromatography, Ion Exchange Colon--chemistry DNA--chemistry Dimethylhydrazines--toxicity Free Radicals Guanine--analogs & derivatives Liver--chemistry Male Rats Rats, Sprague-Dawley Rats, Wistar Spectrometry, Mass, Fast Atom Bombardment Spectrophotometry, Ultraviolet