TY  - GEN
AU  - Rahmani,Mohamed
AU  - Yu,Chunrong
AU  - Reese,Erin
AU  - Ahmed,Wesam
AU  - Hirsch,Karen
AU  - Dent,Paul
AU  - Grant,Steven
TI  - Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21(CIP1/WAF1) induction rather than AKT inhibition
SN  - 0950-9232
PY  - 2003///1031
KW  - Apoptosis
KW  - drug effects
KW  - Benzamides
KW  - pharmacology
KW  - Butyrates
KW  - Chromones
KW  - Complement Membrane Attack Complex
KW  - Complement System Proteins
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Cyclins
KW  - metabolism
KW  - Cytochrome c Group
KW  - Drug Synergism
KW  - Enzyme Inhibitors
KW  - Glycoproteins
KW  - HL-60 Cells
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Jurkat Cells
KW  - K562 Cells
KW  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive
KW  - enzymology
KW  - Mitochondria
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinases
KW  - Morpholines
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Plant Proteins
KW  - Pyridines
KW  - U937 Cells
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/sj.onc.1206646
ER  -