Rahmani, Mohamed <br/><br/>
Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21(CIP1/WAF1) induction rather than AKT inhibition.  [electronic resource] 

 -  Oncogene  Sep 2003 
 - 6231-42 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0950-9232 
<br/><br/><label>Standard No.: </label>10.1038/sj.onc.1206646  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Benzamides--pharmacology<br/>Butyrates--pharmacology<br/>Chromones--pharmacology<br/>Complement Membrane Attack Complex<br/>Complement System Proteins<br/>Cyclin-Dependent Kinase Inhibitor p21<br/>Cyclins--metabolism<br/>Cytochrome c Group--drug effects<br/>Drug Synergism<br/>Enzyme Inhibitors--pharmacology<br/>Glycoproteins--drug effects<br/>HL-60 Cells<br/>Histone Deacetylase Inhibitors<br/>Humans<br/>Jurkat Cells<br/>K562 Cells<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--enzymology<br/>Mitochondria--drug effects<br/>Mitogen-Activated Protein Kinase 1--metabolism<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Morpholines--pharmacology<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Plant Proteins<br/>Pyridines--pharmacology<br/>U937 Cells