TY  - GEN
AU  - Ratcliff,R
AU  - Evans,M J
AU  - Doran,J
AU  - Wainwright,B J
AU  - Williamson,R
AU  - Colledge,W H
TI  - Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting
SN  - 0962-8819
PY  - 1993///0528
KW  - Animals
KW  - Base Sequence
KW  - Blastocyst
KW  - physiology
KW  - Blotting, Southern
KW  - Cloning, Molecular
KW  - Cystic Fibrosis
KW  - genetics
KW  - Cystic Fibrosis Transmembrane Conductance Regulator
KW  - Embryo, Mammalian
KW  - Exons
KW  - Female
KW  - Humans
KW  - Hypoxanthine Phosphoribosyltransferase
KW  - Membrane Proteins
KW  - Mice
KW  - Mice, Transgenic
KW  - Molecular Sequence Data
KW  - Mutagenesis, Insertional
KW  - Oligodeoxyribonucleotides
KW  - Organ Specificity
KW  - Polymerase Chain Reaction
KW  - methods
KW  - Restriction Mapping
KW  - Stem Cells
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/BF02522536
ER  -