TY - GEN AU - Classen,Scott AU - Olland,Stephane AU - Berger,James M TI - Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 SN - 0027-8424 PY - 2003///1029 KW - Adenosine Triphosphatases KW - antagonists & inhibitors KW - Adenosine Triphosphate KW - metabolism KW - Antineoplastic Agents KW - pharmacology KW - Binding Sites KW - DNA Topoisomerases, Type II KW - chemistry KW - Models, Molecular KW - Protein Conformation KW - Razoxane KW - Topoisomerase II Inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.1832879100 ER -