Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Sep 2003
- 10629-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.1832879100 doi
Adenosine Triphosphatases--antagonists & inhibitors Adenosine Triphosphate--metabolism Antineoplastic Agents--pharmacology Binding Sites DNA Topoisomerases, Type II--chemistry Models, Molecular Protein Conformation Razoxane--pharmacology Topoisomerase II Inhibitors