The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes. [electronic resource]
- Human molecular genetics Nov 2003
- 2807-16 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0964-6906
10.1093/hmg/ddg304 doi
Animals COS Cells Chlorocebus aethiops Cycloheximide--pharmacology Dimerization HeLa Cells Humans Intracellular Signaling Peptides and Proteins Lymphocytes--metabolism Mutation Nerve Tissue Proteins--metabolism Nuclear Proteins--metabolism Oncogene Proteins--genetics Parkinson Disease--genetics Protein Deglycase DJ-1 Protein Denaturation Protein Inhibitors of Activated STAT Protein Synthesis Inhibitors--pharmacology Synucleins