A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines. [electronic resource]
- The journal of gene medicine Sep 2003
- 737-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1099-498X
10.1002/jgm.407 doi
Animals Antigens, CD34--immunology Antineoplastic Agents--pharmacology Carmustine--pharmacology Cell Line DNA, Complementary--genetics Drug Resistance, Neoplasm Ferrochelatase--genetics Gene Expression Regulation Gene Expression Regulation, Viral Genetic Therapy Genetic Vectors Green Fluorescent Proteins Humans Lentivirus--genetics Luminescent Proteins--genetics Mice O(6)-Methylguanine-DNA Methyltransferase--genetics Point Mutation Porphyria, Hepatoerythropoietic--genetics Promoter Regions, Genetic T-Lymphocytes--immunology Time Factors Transgenes