TY  - GEN
AU  - Chang,Chang-sheng S
AU  - Olcese,Riccardo
AU  - Olsen,Richard W
TI  - A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation
SN  - 0021-9258
PY  - 2003///1224
KW  - Adjuvants, Anesthesia
KW  - pharmacology
KW  - Allosteric Site
KW  - Amino Acid Sequence
KW  - Anesthetics
KW  - Anesthetics, Intravenous
KW  - Animals
KW  - Cloning, Molecular
KW  - DNA Mutational Analysis
KW  - Dose-Response Relationship, Drug
KW  - Etomidate
KW  - Kinetics
KW  - Ligands
KW  - Models, Biological
KW  - Molecular Sequence Data
KW  - Mutagenesis
KW  - Mutation
KW  - Oocytes
KW  - metabolism
KW  - Patch-Clamp Techniques
KW  - Pentobarbital
KW  - Point Mutation
KW  - Pregnanediones
KW  - Propofol
KW  - Protein Structure, Tertiary
KW  - RNA, Messenger
KW  - Rats
KW  - Receptors, GABA-A
KW  - chemistry
KW  - Recombinant Proteins
KW  - Xenopus
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M306978200
ER  -