Chang, Chang-sheng S

A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation. [electronic resource] - The Journal of biological chemistry Oct 2003 - 42821-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M306978200 doi


Adjuvants, Anesthesia--pharmacology
Allosteric Site
Amino Acid Sequence
Anesthetics--pharmacology
Anesthetics, Intravenous--pharmacology
Animals
Cloning, Molecular
DNA Mutational Analysis
Dose-Response Relationship, Drug
Etomidate--pharmacology
Kinetics
Ligands
Models, Biological
Molecular Sequence Data
Mutagenesis
Mutation
Oocytes--metabolism
Patch-Clamp Techniques
Pentobarbital--pharmacology
Point Mutation
Pregnanediones--pharmacology
Propofol--pharmacology
Protein Structure, Tertiary
RNA, Messenger--metabolism
Rats
Receptors, GABA-A--chemistry
Recombinant Proteins--metabolism
Xenopus