Masubuchi, Yasuhiro

Resistance to indomethacin-induced down-regulation of hepatic cytochrome P450 enzymes in the mice with non-functional Toll-like receptor 4. [electronic resource] - Journal of hepatology Sep 2003 - 349-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0168-8278

10.1016/s0168-8278(03)00244-7 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Aryl Hydrocarbon Hydroxylases--metabolism
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Down-Regulation
Drug Resistance
Endotoxemia--chemically induced
Enzyme Activation--drug effects
Indomethacin--pharmacology
Lipopolysaccharides--pharmacology
Liver--enzymology
Male
Membrane Glycoproteins--metabolism
Membrane Proteins--metabolism
Mice
Mice, Inbred C3H
Mixed Function Oxygenases--antagonists & inhibitors
Peptidoglycan--pharmacology
Receptors, Cell Surface--metabolism
Toll-Like Receptors