TY - GEN AU - Zheng,Jie-Sheng AU - Yang,Xiang-Qun AU - Lookingland,Keith J AU - Fink,Gregory D AU - Hesslinger,Christian AU - Kapatos,Gregory AU - Kovesdi,Imre AU - Chen,Alex F TI - Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension SN - 1524-4539 PY - 2003///1003 KW - Acetophenones KW - therapeutic use KW - Animals KW - Antioxidants KW - Atrasentan KW - Biopterins KW - analogs & derivatives KW - Carotid Arteries KW - drug effects KW - Cyclic N-Oxides KW - Desoxycorticosterone KW - Disease Models, Animal KW - Endothelin Receptor Antagonists KW - Endothelin-1 KW - pharmacology KW - Endothelium, Vascular KW - Enzyme Inhibitors KW - GTP Cyclohydrolase KW - genetics KW - Gene Transfer Techniques KW - Genetic Therapy KW - methods KW - Humans KW - Hypertension KW - chemically induced KW - In Vitro Techniques KW - Male KW - Nitric Oxide KW - metabolism KW - Pyrrolidines KW - Rats KW - Rats, Sprague-Dawley KW - Receptor, Endothelin A KW - Sodium Chloride KW - Spin Labels KW - Superoxides KW - Vasodilation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1161/01.CIR.0000089082.40285.C3 ER -