Zheng, Jie-Sheng

Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension. [electronic resource] - Circulation Sep 2003 - 1238-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1524-4539

10.1161/01.CIR.0000089082.40285.C3 doi


Acetophenones--therapeutic use
Animals
Antioxidants--therapeutic use
Atrasentan
Biopterins--analogs & derivatives
Carotid Arteries--drug effects
Cyclic N-Oxides--therapeutic use
Desoxycorticosterone
Disease Models, Animal
Endothelin Receptor Antagonists
Endothelin-1--pharmacology
Endothelium, Vascular--drug effects
Enzyme Inhibitors--pharmacology
GTP Cyclohydrolase--genetics
Gene Transfer Techniques
Genetic Therapy--methods
Humans
Hypertension--chemically induced
In Vitro Techniques
Male
Nitric Oxide--metabolism
Pyrrolidines--pharmacology
Rats
Rats, Sprague-Dawley
Receptor, Endothelin A
Sodium Chloride
Spin Labels
Superoxides--metabolism
Vasodilation--drug effects