TY - GEN AU - Zhang,Da-Wei AU - Gu,Hong-Mei AU - Vasa,Monika AU - Muredda,Mario AU - Cole,Susan P C AU - Deeley,Roger G TI - Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3 SN - 0006-2960 PY - 2003///1001 KW - ATP Binding Cassette Transporter, Subfamily B KW - chemistry KW - ATP-Binding Cassette Transporters KW - Amino Acid Sequence KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Biological Transport KW - Cell Division KW - drug effects KW - Cell Line KW - Cell Membrane KW - metabolism KW - DNA Primers KW - Drug Resistance, Multiple KW - Enzyme Inhibitors KW - Estradiol KW - analogs & derivatives KW - Etoposide KW - Humans KW - Hydrogen Bonding KW - Kinetics KW - Leukotriene C4 KW - Methotrexate KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Mutation KW - genetics KW - Polymerase Chain Reaction KW - Sequence Homology, Amino Acid KW - Structure-Activity Relationship KW - Substrate Specificity KW - Taurocholic Acid KW - Transfection N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi034462b ER -