TY - GEN AU - Piao,Chun Shu AU - Kim,Jung-Bin AU - Han,Pyung-Lim AU - Lee,Ja-Kyeong TI - Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult SN - 0360-4012 PY - 2003///0908 KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - therapeutic use KW - Astrocytes KW - drug effects KW - Blotting, Western KW - methods KW - Brain KW - Brain Infarction KW - metabolism KW - Cyclooxygenase 2 KW - Cytokines KW - genetics KW - Disease Models, Animal KW - Gene Expression Regulation KW - Imidazoles KW - Immunohistochemistry KW - Infarction, Middle Cerebral Artery KW - physiopathology KW - Isoenzymes KW - Lectins KW - Male KW - Microglia KW - Mitogen-Activated Protein Kinase 14 KW - Mitogen-Activated Protein Kinases KW - antagonists & inhibitors KW - Neurologic Examination KW - Nitric Oxide Synthase KW - Nitric Oxide Synthase Type II KW - Prostaglandin-Endoperoxide Synthases KW - Pyridines KW - RNA, Messenger KW - biosynthesis KW - Rats KW - Rats, Sprague-Dawley KW - Reverse Transcriptase Polymerase Chain Reaction KW - Tetrazolium Salts KW - Time Factors N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jnr.10671 ER -