The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse. [electronic resource]
- The Journal of clinical investigation Jul 2003
- 170-80 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI16603 doi
Animals Antineoplastic Agents--pharmacology Cell Division Cell Line DNA-Binding Proteins--genetics Dose-Response Relationship, Drug Flow Cytometry Gene Expression Regulation Gene Transfer Techniques Immunoblotting Immunohistochemistry Interferon-alpha--pharmacology Killer Cells, Natural Mice Mice, Inbred C57BL Mice, SCID Mice, Transgenic Retroviridae--genetics STAT1 Transcription Factor Signal Transduction Spleen--cytology Time Factors Trans-Activators--genetics Tumor Cells, Cultured