Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. [electronic resource]
- The Journal of biological chemistry Oct 2003
- 39092-103 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M301749200 doi
Animals Antiviral Agents--pharmacology Automation Carbamates--chemistry Cells, Cultured Chromatography, Gas Dose-Response Relationship, Drug Fluorescence Resonance Energy Transfer Gene Products, tat--chemistry HIV-1--chemistry HeLa Cells Humans Ligands Mice Models, Biological Models, Chemical Models, Statistical Nucleic Acid Conformation Oligopeptides--chemistry Peptide Library Protein Binding RNA--chemistry RNA-Directed DNA Polymerase--metabolism Structure-Activity Relationship Transcriptional Activation tat Gene Products, Human Immunodeficiency Virus