TY - GEN AU - Huang,Zhi-Li AU - Sato,Yo AU - Mochizuki,Takatoshi AU - Okada,Tetsuya AU - Qu,Wei-Min AU - Yamatodani,Atsushi AU - Urade,Yoshihiro AU - Hayaishi,Osamu TI - Prostaglandin E2 activates the histaminergic system via the EP4 receptor to induce wakefulness in rats SN - 1529-2401 PY - 2003///0807 KW - Animals KW - Dinoprostone KW - pharmacology KW - Dose-Response Relationship, Drug KW - Frontal Lobe KW - drug effects KW - Histamine KW - analysis KW - Histidine Decarboxylase KW - genetics KW - Hypothalamic Area, Lateral KW - cytology KW - Hypothalamus KW - Male KW - Methyl Ethers KW - Microdialysis KW - Neurons KW - Perfusion KW - Preoptic Area KW - RNA, Messenger KW - metabolism KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Prostaglandin E KW - agonists KW - Receptors, Prostaglandin E, EP4 Subtype KW - Wakefulness N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -