Asikainen, Arja

Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes. [electronic resource] - Toxicology in vitro : an international journal published in association with BIBRA Aug 2003 - 449-55 p. digital

Publication Type: Comparative Study; Journal Article

0887-2333

10.1016/s0887-2333(03)00065-1 doi


Animals
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Cytochrome P-450 CYP2A6
Cytochrome P450 Family 2
Enzyme Inhibitors--pharmacology
Female
Humans
Hydroxylation
Kinetics
Male
Mice
Mice, Inbred DBA
Microsomes, Liver--drug effects
Mixed Function Oxygenases--antagonists & inhibitors
Models, Biological
NADP--metabolism
Naphthalenes--pharmacology
Oxidation-Reduction
Predictive Value of Tests