TY  - GEN
AU  - Matthews,Vance
AU  - Schuster,Björn
AU  - Schütze,Stefan
AU  - Bussmeyer,Ingo
AU  - Ludwig,Andreas
AU  - Hundhausen,Christian
AU  - Sadowski,Thorsten
AU  - Saftig,Paul
AU  - Hartmann,Dieter
AU  - Kallen,Karl-Josef
AU  - Rose-John,Stefan
TI  - Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
SN  - 0021-9258
PY  - 2003///1106
KW  - ADAM Proteins
KW  - ADAM10 Protein
KW  - ADAM17 Protein
KW  - Acetophenones
KW  - pharmacology
KW  - Alternative Splicing
KW  - Amyloid Precursor Protein Secretases
KW  - Animals
KW  - Benzopyrans
KW  - Blotting, Western
KW  - COS Cells
KW  - Cell Line
KW  - Cell Membrane
KW  - metabolism
KW  - Ceramides
KW  - Cholesterol
KW  - Cyclodextrins
KW  - Dimerization
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Activation
KW  - Enzyme Inhibitors
KW  - Enzyme-Linked Immunosorbent Assay
KW  - Fibroblasts
KW  - Humans
KW  - Interleukin-6
KW  - Lipid Metabolism
KW  - Membrane Proteins
KW  - Metalloendopeptidases
KW  - Mice
KW  - Mice, Transgenic
KW  - Monocytes
KW  - Precipitin Tests
KW  - Protein Kinase C
KW  - Protein Structure, Tertiary
KW  - Receptors, Interleukin-6
KW  - Sphingomyelins
KW  - Staurosporine
KW  - Time Factors
KW  - Transfection
KW  - beta-Cyclodextrins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M210584200
ER  -