Matthews, Vance <br/><br/>
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE).  [electronic resource] 

 -  The Journal of biological chemistry  Oct 2003 
 - 38829-39 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M210584200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ADAM Proteins<br/>ADAM10 Protein<br/>ADAM17 Protein<br/>Acetophenones--pharmacology<br/>Alternative Splicing<br/>Amyloid Precursor Protein Secretases<br/>Animals<br/>Benzopyrans--pharmacology<br/>Blotting, Western<br/>COS Cells<br/>Cell Line<br/>Cell Membrane--metabolism<br/>Ceramides--metabolism<br/>Cholesterol--metabolism<br/>Cyclodextrins--metabolism<br/>Dimerization<br/>Dose-Response Relationship, Drug<br/>Enzyme Activation<br/>Enzyme Inhibitors--pharmacology<br/>Enzyme-Linked Immunosorbent Assay<br/>Fibroblasts--metabolism<br/>Humans<br/>Interleukin-6--metabolism<br/>Lipid Metabolism<br/>Membrane Proteins--metabolism<br/>Metalloendopeptidases--metabolism<br/>Mice<br/>Mice, Transgenic<br/>Monocytes--metabolism<br/>Precipitin Tests<br/>Protein Kinase C--metabolism<br/>Protein Structure, Tertiary<br/>Receptors, Interleukin-6--metabolism<br/>Sphingomyelins--metabolism<br/>Staurosporine--pharmacology<br/>Time Factors<br/>Transfection<br/>beta-Cyclodextrins