deSolms, S Jane <br/><br/>
Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.  [electronic resource] 

 -  Journal of medicinal chemistry  Jul 2003 
 - 2973-84 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm020587n  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkyl and Aryl Transferases--antagonists & inhibitors<br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Carrier Proteins--metabolism<br/>Crystallography, X-Ray<br/>Drug Screening Assays, Antitumor<br/>HSP40 Heat-Shock Proteins<br/>Heat-Shock Proteins--metabolism<br/>Humans<br/>Mice<br/>Mice, Nude<br/>Models, Molecular<br/>Neoplasm Transplantation<br/>Neoplasms, Experimental--drug therapy<br/>Protein Prenylation<br/>Structure-Activity Relationship<br/>Transplantation, Heterologous<br/>Tumor Cells, Cultured<br/>rap1 GTP-Binding Proteins--metabolism<br/>ras Proteins--metabolism