Wagner, Carl E

Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81. [electronic resource] - Journal of medicinal chemistry Jul 2003 - 2823-33 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm020326d doi


Adamantane--analogs & derivatives
Animals
Antigens, CD--metabolism
Antineoplastic Agents--chemical synthesis
Antiviral Agents--chemical synthesis
Astrocytes--cytology
Boron Compounds--chemical synthesis
Crystallography, X-Ray
Dose-Response Relationship, Drug
Glioma
Hepacivirus--drug effects
Membrane Proteins--deficiency
Models, Molecular
Protein Binding
Rats
Structure-Activity Relationship
Tetraspanin 28
Tumor Cells, Cultured