Kobayashi, Kaoru

Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Jul 2003 - 833-6 p. digital

Publication Type: Journal Article

0090-9556

10.1124/dmd.31.7.833 doi


Aniline Compounds--pharmacology
Animals
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Cytochrome P-450 CYP1A2--drug effects
Cytochrome P-450 CYP1A2 Inhibitors
Cytochrome P-450 CYP2E1--drug effects
Cytochrome P-450 CYP2E1 Inhibitors
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--drug effects
Cytochrome P450 Family 2
DNA, Complementary--genetics
Enzyme Inhibitors
Gene Expression--genetics
Humans
Isoenzymes--drug effects
Ketoconazole--pharmacology
Methoxsalen--pharmacology
Microsomes, Liver--enzymology
Quinidine--pharmacology
Rats
Steroid 16-alpha-Hydroxylase--antagonists & inhibitors
Steroid 21-Hydroxylase--antagonists & inhibitors
Steroid Hydroxylases
Substrate Specificity--drug effects
Sulfaphenazole--pharmacology
Theophylline--analogs & derivatives