Kobayashi, Kaoru
Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. [electronic resource]
- Drug metabolism and disposition: the biological fate of chemicals Jul 2003
- 833-6 p. digital
Publication Type: Journal Article
ISSN: 0090-9556
Standard No.: 10.1124/dmd.31.7.833 doi
Subjects--Topical Terms: Aniline Compounds--pharmacology Animals Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors Cytochrome P-450 CYP1A2--drug effects Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP2E1--drug effects Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System--drug effects Cytochrome P450 Family 2 DNA, Complementary--genetics Enzyme Inhibitors Gene Expression--genetics Humans Isoenzymes--drug effects Ketoconazole--pharmacology Methoxsalen--pharmacology Microsomes, Liver--enzymology Quinidine--pharmacology Rats Steroid 16-alpha-Hydroxylase--antagonists & inhibitors Steroid 21-Hydroxylase--antagonists & inhibitors Steroid Hydroxylases Substrate Specificity--drug effects Sulfaphenazole--pharmacology Theophylline--analogs & derivatives