TY  - GEN
AU  - Bolger,Graeme B
AU  - Peden,Alexander H
AU  - Steele,Michael R
AU  - MacKenzie,Carolynn
AU  - McEwan,David G
AU  - Wallace,Derek A
AU  - Huston,Elaine
AU  - Baillie,George S
AU  - Houslay,Miles D
TI  - Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2
SN  - 0021-9258
PY  - 2003///1002
KW  - 1-Methyl-3-isobutylxanthine
KW  - pharmacology
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - chemistry
KW  - Alanine
KW  - Amino Acid Sequence
KW  - Animals
KW  - COS Cells
KW  - Cloning, Molecular
KW  - Colforsin
KW  - Cyclic AMP
KW  - metabolism
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - DNA, Complementary
KW  - Dose-Response Relationship, Drug
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Gene Deletion
KW  - Glutathione Transferase
KW  - Humans
KW  - Immunoblotting
KW  - Inhibitory Concentration 50
KW  - Intracellular Signaling Peptides and Proteins
KW  - Molecular Sequence Data
KW  - Mutation
KW  - Open Reading Frames
KW  - Phosphorylation
KW  - Precipitin Tests
KW  - Protein Binding
KW  - Protein Isoforms
KW  - Protein Structure, Tertiary
KW  - Proteins
KW  - Rats
KW  - Recombinant Fusion Proteins
KW  - Rolipram
KW  - Saccharomyces cerevisiae
KW  - Sequence Homology, Amino Acid
KW  - Time Factors
KW  - Two-Hybrid System Techniques
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M303269200
ER  -