TY - GEN AU - Zhang,Lin AU - Yang,Nuo AU - Park,Jin-Wan AU - Katsaros,Dionyssios AU - Fracchioli,Stefano AU - Cao,Gaoyuan AU - O'Brien-Jenkins,Ann AU - Randall,Thomas C AU - Rubin,Stephen C AU - Coukos,George TI - Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer SN - 0008-5472 PY - 2003///0728 KW - Angiogenesis Inducing Agents KW - biosynthesis KW - Angiopoietin-1 KW - Angiopoietin-2 KW - Animals KW - Carcinoma KW - blood supply KW - Cell Line, Transformed KW - drug effects KW - Dactinomycin KW - pharmacology KW - Endothelial Growth Factors KW - Endothelium, Vascular KW - Female KW - Gene Expression Regulation, Neoplastic KW - Genes, Reporter KW - Humans KW - Intercellular Signaling Peptides and Proteins KW - Lymphokines KW - Membrane Glycoproteins KW - Mice KW - Mice, Inbred C57BL KW - Models, Biological KW - Neoplasm Proteins KW - Neovascularization, Pathologic KW - physiopathology KW - Nucleic Acid Synthesis Inhibitors KW - Ovarian Neoplasms KW - Paracrine Communication KW - Pericytes KW - pathology KW - RNA, Messenger KW - RNA, Neoplasm KW - Receptor Protein-Tyrosine Kinases KW - Receptor, TIE-2 KW - Recombinant Fusion Proteins KW - Stromal Cells KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -