Zhang, Lin

Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. [electronic resource] - Cancer research Jun 2003 - 3403-12 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0008-5472


Angiogenesis Inducing Agents--biosynthesis
Angiopoietin-1
Angiopoietin-2
Animals
Carcinoma--blood supply
Cell Line, Transformed--drug effects
Dactinomycin--pharmacology
Endothelial Growth Factors--pharmacology
Endothelium, Vascular--drug effects
Female
Gene Expression Regulation, Neoplastic
Genes, Reporter
Humans
Intercellular Signaling Peptides and Proteins--pharmacology
Lymphokines--pharmacology
Membrane Glycoproteins--biosynthesis
Mice
Mice, Inbred C57BL
Models, Biological
Neoplasm Proteins--biosynthesis
Neovascularization, Pathologic--physiopathology
Nucleic Acid Synthesis Inhibitors--pharmacology
Ovarian Neoplasms--blood supply
Paracrine Communication
Pericytes--pathology
RNA, Messenger--biosynthesis
RNA, Neoplasm--biosynthesis
Receptor Protein-Tyrosine Kinases--biosynthesis
Receptor, TIE-2
Recombinant Fusion Proteins--biosynthesis
Stromal Cells--drug effects
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factors